Champions Oncology Workshop Series

Champions Oncology Paris Workshop

Event Details

Date: Wednesday 4th March 2020
Time: 11:00-14:00 Local Time
City: Paris, France
Venue: Regus – Paris Montparnasse
140 bis Rue de Rennes
75006 Paris

Schedule

11:00 – 12:00: Workshop 1 – Utilizing PDX Models to Guide Clinical Trial Design

12:00 – 13:00: Networking Lunch

13:00 – 14:00: Workshop 2 – Immuno-Oncology 2.0: Latest Humanised Models for Preclinical Research

Workshop Details

Workshop 1:

  • How to achieve better, smarter PDX model selection with advanced bioinformatics tools
  • What study type and design for what developmental questions
  • N=1 vs n=10: how to power in vivo PDX studies effectively and reduce animal use
  • Ex vivo vs in vivo: what to choose, and at what stage of the drug development pipeline

Workshop 2:

  • Latest humanised mouse models for pharmacodynamic and efficacy assessment of immunotherapies
  • T-cells, Regulatory T-Cells, Macrophages, Natural Killer cells, Dendritic cells: how to reconstitute a full human system in mouse and to model complex immune mechanisms in vivo
  • PBMC vs CD34+ Hematopoietic Stem Cells: what type of humanisation for what applications
  • Cell line xenograft vs PDX in humanised mouse studies: pros and cons

The event is free to attend, but seats are limited.

Please Register Today!