Patient Matched Clinical Trials

Matched Patient PDX Clinical TrialsPatient Matched PDX Models – Response Data to Guide Clinical Trial Enrollment

Patient Matched PDX models involve developing PDX models from clinical patients to direct their enrollment in a clinical trial based on the PDX evaluation, or a possible future therapy.

Patients are screened and selected for PDX development based on tumor type or molecular characterization and treated with standards of care by their oncologist.  

During that time, a PDX model is developed and tested for response with multiple drug/drug combinations, yielding simultaneous relative response data.  Based on the drug responses in the PDX model, patients are enrolled in the most suitable human clinical trial.

The patient-matched Champions TumorGrafts can also be preserved for future testing.

Contact us to learn more about ensuring successful clinical trials by using patient-matching PDX models by Champions Oncology.