Clinical Flow Cytometry

Champions Oncology Clinical SolutionsClinical Flow Cytometry Solutions for Drug Discovery and Development

Flow cytometry has become a powerful and versatile tool for medical innovation in Immuno-Oncology and Hematology-Oncology drug development by providing in-depth insight into immune cell signaling and behavior.

Champions Oncology provides high-quality, multi-parameter flow cytometry testing and analysis to support preclinical and clinical trials programs.

Our sophisticated training programs ensure quality sample recovery.

Operating under CLIA regulations, specialized flow cytometry scientists perform all assays in our state of the art laboratory, and work closely with our partners to meet any necessary GCP requirements.  Champions Oncology validated offers laboratory developed panels, or leverage our ability to tailor existing panels or customize new ones to meet specific study needs.

From consultative study and panel design to site management and training and specialized reporting/data transfer, Champions Oncology delivers the flow cytometry data necessary to answer your unique questions.

Contact us about Champion Oncology flow cytometry service solutions.

Adding Flow Cytometry to Your Study

The advantages of Champions Oncology flow cytometry service solutions are apparent long before the first sample is analyzed. Champions Oncology’s highly skilled team of flow Cytometry specialists initiate each partnership by developing a total solution, from standard or custom panel design or reporting and timing that meets your unique requirements.

Champions Oncology optimizes the sample preparation process with in-depth site training and management to ensure the collection of high quality samples for analysis, including PBMCs, bone marrow and cryopreservation. Training delivery options include live sessions delivered online, pre-recorded modules or the use of comprehensive training manuals, depending on your needs.

Operating under CLIA regulations, highly skilled flow cytometry scientists perform all assays. Champions Oncology’s validated laboratory developed assays can be customized to meet program objectives. All data sets are captured in the Champions Oncology customized LIMS system, which has the ability to provide extended assessment of immune system modulation and cellular response with a cohort of samples at a given point in time and the additional capacity of longitudinally tracking serial sample responses over time.

Champions Oncology ensures information security by supporting database lock, securing data transfer and audit trail report.

  • Encrypted USB
  • Cloud-based secure transfer
  • Encrypted email
  • Data can also be formatted to utilize client data platform

Contact us to develop a total flow cytometry solution with Champions Oncology.

Flow Cytometry Assays

Champions Oncology’s flow cytometry services provide characterization of a wide range of adaptive and innate immune cell subsets. Champions has over 10 years’ experience of handling patient samples. Our CLIA-certified cytometry panels can be used to identify specific markers in both lymphoid and myeloid cell populations, as well as cells associated with humoral or cell-mediated immune response.

  • TBNK assay (T-cell, B-cell, NK-cell)
  • Leukocyte activation and profiling panels
  • T-Helper cell panel (Designate Th1 Th2 Th17)
  • Monocytes (Myeloid, Macrophages) [TAMS/MDSCs]
  • Dendritic cell panel (Adaptive Immunity)
  • T cell effector panel
  • Cytotoxic T cell activation panel
  • T cell receptor subset panel
  • T Reg receptor subset panel
  • Cytotoxic T cell receptor subset panel
  • AML panel

In addition, a key Champions Oncology capability is the development of new panels based on our client’s specific needs. Leveraging the performance of the BD FACSLyric and Miltenyi MACSQuant, analyzers, and our flow cytometry specialist team, Champions Oncology removes the complexity of custom panel design. Customers have the option of developing custom panels for non-clinical CLIA use, validating the assay under CLIA, or for initial use in preclinical research and subsequent validation for clinical trials.

Champions Oncology also offers flexibility in reporting formats and timing.

Decision support tools available from Champions Oncology Flow Cytometry services include longitudinal assessments of immune system modulation, enabled by our custom validated LIMS system. Champions Oncology has the ability to map series of samples to specific, individual patients for correlation of immune system profiles and clinical response over time.

Learn more about meeting your cytometric assay development, analysis, and validation needs with Champions Oncology.