Clinically Relevant Models
Living & diverse bank of clinically relevant models that correlate with clinical outcomes
Pretreated PDX Models
Established from tumor biopsies from patients pretreated with latest generation therapies
Multi-omic Characterization
Clinical annotations coupled with molecular datasets and in vivo responses
Transform your Head & Neck Cancer Drug Development Research
Champions' Head & Neck (HNSCC) Cancer PDX Models represent a premier cohort designed to advance the discovery of breakthrough therapies for head and neck cancers. With one of the industry's largest banks of HNSCC models, this collection includes 125* Patient-Derived Xenograft (PDX) models that preserve critical clinical and molecular characteristics, mutation profiles, and pretreated models exposed to the latest cancer therapies, offering a powerful platform to evaluate the efficacy and therapeutic potential of drug candidates. (*Model numbers fluctuate as our dataset continuously evolves.)
Champions' leading Head & Neck Cancer In Vivo Screen showcases low-passage PDX models, each reflecting key clinical characteristics, mutations, and pretreatment history.
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Access one of the largest banks of HNSCC models with clinically relevant molecular
and pathological characteristics on the market. -
Includes models pretreated with advanced cancer therapies and those resistant to targeted treatments and the latest immunotherapies targeting CDK4, PI3K, and EGFR.
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Access to highly characterized HNSCC models with High Complexity Flow Cytometry, WES, RNAseq, Proteomics, and Phosphoproteomics.
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Features models retaining key mutation profiles and clinical cancer characteristics, such as models that are HPV16+ and/or HPV18+.