A Comparison of using Matrix in 3D Ex Vivo Tissue Cultures

TumorGraft3D models are Champions’ three-dimensional (3D) ex vivo tissue cultures that mimic the structure and function of tumors in vivo.

TumorGraft3D models can be derived from various tissues, such as the brain, liver, intestine, etc., and can self-organize into complex structures resembling their respective tumor locations. However, the establishment and growth of 3D tissue culture models require the model to interact with the myriad of cellular and structural components within the tumor microenvironment.

In this infographic, we will explore the differences between using matrix or matrix-free assays in 3D tissue cultures.