How It Works


A piece of the patient’s living tumor is removed during surgery or biopsy and is implanted in mice. By implanting the tumor together with its microenvironment, Champions TumorGraft tumor models continue to very closely resemble the patient’s tumor, with 94 percent genetic correlation to the tumor in the patient. Approximately 70 percent of implanted tumors grow successfully in mice.

TumorGraft Process


While the Champions TumorGraft patient-derived xenograft (PDX) models are growing in the mice, the patient continues to receive regular cancer treatment therapy from their oncologist. This growth period generally takes two months or longer.


Our scientists work closely with treating physicians to determine which cancer drugs to test on the patient’s PDX model. Our labs will administer these cancer treatments to the mice and measure the living tumor’s response to each drug regimen. Physicians receive a robust report on the effectiveness of each tested cancer therapy on the PDX models. With this information in hand, physicians can personalize each patient’s cancer treatment therapy.


Every Champions TumorGraft®  PDX model  is preserved as a living sample for future patient use. These banked PDX models can be regrown and tested in the event of cancer progression or recurrence.

The entire process (implantation through testing) typically takes 12-16 weeks.

No matter where you are in your diagnosis, you can keep your tumor — and your hopes — alive by sending your tumor to Champions.

Read about Our Experience >

Champions Oncology - Specializing in | Personalized Cancer Therapy | Translational Oncology Solutions | Oncology drug development | Oncology drug discovery | Translational oncology | Translation oncology research | Predictive oncology | Patient-derived xenograft model | Tumorgrafts | Alternative/new cancer treatment | Anticancer therapies | Personalized cancer treatment | Personalized cancer therapy | Personalized oncology